Abstract
The purpose of the research is studying the duration of the chemoprophylactic effect of prolonged solutions of DAC (diminazene aceturate) in combination with a solution of glycerin in bovine pyroplasmidoses.Materials and methods. 300 cattle were examined at the farms of the Kizilyurt and Kumtorkalinsky Districts of the Republic of Dagestan for tick infection. 45 blood smears were examined. Three groups of animals of 15 animals each were formed according to the principle of analogues. The first control group was administered DAC without glycerol, and the experimental groups were given prolonged solutions of DAC in combination with glycerin 10–12 days after the animals were sent to the pasture with rare solutions of acaricides during the mass tick infection period. The drug was administered intramuscularly at a dose of 4–5 ml per 100 kg of body weight. Animals were observed during the season; in case of any change in general condition, thermometry was performed, and blood smears were examined.Results and discussion. 5% aqueous solution of DAC in combination with a solution of glycerol provides prophylaxis of pyroplasmidoses in cattle. The chemoprophylactic effect of 5 % aqueous glycerol solution of DAC is kept in the animal body for 25 days. Its 6 times' use ensures the well-being of animals during the season (from April to September).
Highlights
The chemoprophylactic effect of 5 % aqueous glycerol solution of DAC is kept in the animal body for 25 days
РАН «Теория и практика борьбы с паразитарными болезнеями»
Summary
Химиопрофилактика пироплазмидозов крупного рогатого скота в условиях Республики Дагестан. Цель исследований: изучение продолжительности химиопрофилактического действия пролонгированных растворов ДАЦ (диминацена ацетурата) в сочетании с раствором глицерина при пироплазмидозах крупного рогатого скота. Обследовано 300 голов крупного рогатого скота в хозяйствах Кизилюртовского и Кумторкалинского районов Республики Дагестан на пораженность клещами. Первой контрольной группе ДАЦ вводили без глицерина, подопытным группам – пролонгированные растворы ДАЦ в сочетании с глицерином через 10–12 сут после выгона животных на пастбище с разреженными обработками растворами акарицидов в период массовой заклещеванности. В течение сезона за животными вели наблюдения; при изменении в общем состоянии проводили термометрию и исследовали мазки крови. 5%-ный водный раствор ДАЦ в сочетании с раствором глицерина обеспечивает профилактику пироплазмидозов у крупного рогатого скота. Химиопрофилактическое действие 5%-ного водно-глицеринового раствора ДАЦ сохраняется в организме животных в течение 25 сут. М. Химиопрофилактика пироплазмидозов крупного рогатого скота в условиях Республики Дагестан // Российский паразитологический журнал.
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