Hemodynamic Evaluation of Exercise Treadmill Test by a Computer-Aided Clinical Decision System

Abstract

By applying a clinical decision system, introduced as the Noninvasive Hemodynamic Analyzer (NHA) system, to demonstrate its capability to compute the hemodynamic status of exercising patients. Retrospective study to use the average vital signs and anthropological data of a large clinical trial of exercise treadmill test. The NHA system computes the percent abnormal hemodynamic parameters and these results are compared to the percent clinical classification of coronary artery disease of the Seattle Heart Watch clinical study. Four groups of the clinical study (1) Healthy, (2) Hypertensive, (3) Angina Pectoris, and (4) Postmyocardial Infarction, were used and comprised the average data of several hundred patients. Each group had three subgroups according to the conducted exercise treadmill test, namely one upright and two exercise tests. In this study the statistical evaluation was not available because the average values did not permit it. Instead, we have chosen to compute the abnormal hemodynamic parameters according to the ideal values at the level of ±20%. Altogether 33 hemodynamic parameters were included and the abnormal values were expressed in percentage. The percent cumulative abnormal responses of each hemodynamic profile obtained by the Noninvasive Hemodynamic Analyzer system as compared to the published percent clinical classification of coronary artery disease of the Seattle Heart Watch clinical study was closely matched in all clinical groups. The results of this retrospective study prove that the hemodynamic computation of the NHA system is a valid approach to evaluate exercise treadmill tests.