Hemifasiyal Spazm Hastalarında Kafein Kullanımının Etkileri

Abstract

Abstract
 Objective: Hemifacial spasm is characterized by progressive, involuntary, irregular contraction of the muscles innervated by the facial nerve. Caffeine is a phytochemical that increases muscle contraction and neurotransmitter release. The aim of this study is to evaluate the effects of caffeine-containing food consumption on disease severity and disease-related quality of life in patients with hemifacial spasm. 
 Materials and Methods: In hemifacial spasm patients who applied to the neurology outpatient clinic; hemifacial spasm quality of life scale and hemifacial spasm severity scale were evaluated prospectively. The amount of caffeine taken by the patients with daily food and beverage was determined. The relationship between the results of the scales and the amount of caffeine consumed was analyzed.
 Results: A total of 60 patients, 36 women (60%) and 24 men (40%), were included in the study. It was determined that 59 of the patients (98.3%) consumed an average of 303±144 mg/day of caffeine with food. The hemifacial spasm quality of life scale score was calculated as 8.5 (4-21) and the hemifacial spasm severity scale was calculated as 3 (1-4). No significant correlation was found between the amount of caffeine consumed by gender (p=0.066). A negative correlation was found between the amount of caffeine consumed by age (r=-0.291; p=0.024). There was no significant relationship between daily caffeine consumption and hemifacial spasm quality of life scale and hemifacial spasm severity (p values 0.297 and 0.839, respectively). There is a weak positive correlation between the hemifacial spasm quality of life scale and the severity of hemifacial spasm (r=0.291; p=0.024).
 Conclusion: It has been determined that the consumption of foods containing caffeine in daily life does not affect the severity of spasm and quality of life in patients with hemifacial spasm.