Abstract
Evidence from epidemiological studies reported that height was inversely associated with cardiovascular diseases, but the association between height and hypertension was unclear. The purpose of this study was to explore the association between height and blood pressure or prevalence of hypertension in a middle-aged and older Chinese population. A total of 33,197 participants aged 37 to 94 years were recruited from the Dongfeng-Tongji cohort study in Hubei province, China. All participants completed baseline questionnaires, medical examinations and provided blood samples. Hypertension was define as a systolic blood pressure (SBP) over 140 mmHg or/and a diastolic blood pressure (DBP) over 90 mmHg, or current use of antihypertensive medication, or participants with self-reported physician diagnosis of hypertension. Multivariate linear and logistic regression models were used. The prevalence of hypertension was 69.1% for men and 58.0% for women. Pulse pressure (PP) and SBP, but not DBP decreased linearly with increasing height among men and women. Comparing the highest with the shortest quartile of height, the multivariate-adjusted odds ratios were 0.80 (95% confidence interval, 0.71, 0.91) for men and 0.83 (0.74, 0.92) for women. In conclusion, height was associated with reduced SBP, PP and prevalence of hypertension in a middle-aged and older Chinese population.
Highlights
In this cross-sectional study, we found that height was associated with lower SBP and PP but not with DBP independent of potential confounders
We observed a dose-dependent association between height and prevalence of hypertension after controlling for potential confounders, suggesting that height was associated with a reduced prevalence of hypertension
A population-based cohort study of 20,007 individuals aged between 40 and 70 years reported that shorter height in elderly was correlated with an increased risk of hypertension independent of antihypertensive medications; a finding that was in line with our results[16]
Summary
The purpose of this study was to explore the association between height and blood pressure or prevalence of hypertension in a middle-aged and older Chinese population. The aim of the present study was to examine the association between height and the prevalence of hypertension in a middle-aged and older Chinese population after adjustment for potential confounders
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