Abstract

Physiological time series are affected by many factors, making them highly nonlinear and nonstationary. As a consequence, heart rate time series are often considered difficult to predict and handle. However, heart rate behavior can indicate underlying cardiovascular and respiratory diseases as well as mood disorders. Given the importance of accurate modeling and reliable predictions of heart rate fluctuations for the prevention and control of certain diseases, it is paramount to identify models with the best performance in such tasks. The objectives of this study were to compare the results of three different forecasting models (Autoregressive Model, Long Short-Term Memory Network, and Convolutional Long Short-Term Memory Network) trained and tested on heart rate beats per minute data obtained from twelve heterogeneous participants and to identify the architecture with the best performance in terms of modeling and forecasting heart rate behavior. Heart rate beats per minute data were collected using a wearable device over a period of 10 days from twelve different participants who were heterogeneous in age, sex, medical history, and lifestyle behaviors. The goodness of the results produced by the models was measured using both the mean absolute error and the root mean square error as error metrics. Despite the three models showing similar performance, the Autoregressive Model gave the best results in all settings examined. For example, considering one of the participants, the Autoregressive Model gave a mean absolute error of 2.069 (compared to 2.173 of the Long Short-Term Memory Network and 2.138 of the Convolutional Long Short-Term Memory Network), achieving an improvement of 5.027% and 3.335%, respectively. Similar results can be observed for the other participants. The findings of the study suggest that regardless of an individual’s age, sex, and lifestyle behaviors, their heart rate largely depends on the pattern observed in the previous few minutes, suggesting that heart rate can be reasonably regarded as an autoregressive process. The findings also suggest that minute-by-minute heart rate prediction can be accurately performed using a linear model, at least in individuals without pathologies that cause heartbeat irregularities. The findings also suggest many possible applications for the Autoregressive Model, in principle in any context where minute-by-minute heart rate prediction is required (arrhythmia detection and analysis of the response to training, among others).

Highlights

  • Heart rate (HR) behavior is correlated with many underlying conditions and pathologies, including the risk of cardiovascular diseases [1], anxiety and depression [2,3], and asthma or breathing problems [4]

  • Luo and Wu [6] previously performed a similar study; unlike them, this study only considered information provided by the univariate HR time series to show that the prediction results are sufficient in the absence of other physiological information on the individual, which may not be available

  • As described in the Materials and Methods section, autocorrelation function (ACF) and partial autocorrelation function (PACF) plots were analyzed to select an appropriate order for the AR model

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Summary

Introduction

Heart rate (HR) behavior is correlated with many underlying conditions and pathologies, including the risk of cardiovascular diseases [1], anxiety and depression [2,3], and asthma or breathing problems [4]. The ability to reliably and effectively predict HR fluctuations has great significance and implications for the prevention and control of some cardiovascular diseases [6]. Physiological time series are affected by many factors, making them highly nonlinear and nonstationary. HR time series are often considered difficult to predict and handle. Christini et al [7] analyzed HR dynamics and compared the performance of linear autoregressive (AR) models and linear autoregressive-moving average (ARMA) models with nonlinear models (such as the polynomial autoregressive model) and bilinear models when fitting

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