Abstract

Heart failure 2012.

Highlights

  • The transcription factor (STAT3) is an important mediator of the inflammatory process, and in this original research the investigators examine the role of signal transducer and activator of transcription 3 (STAT3) in viral myocarditis and its possible role in the development to dilated cardiomyopathy

  • Cognitive impairment is increasingly recognized as Cardiology Research and Practice a common adverse consequence of HF, whereby phenomena such as microembolism, chronic or intermittent cerebral hypoperfusion, and/or impaired cerebral vessel reactivity may lead to cerebral hypoxia and ischemic brain damage

  • Current research is supporting the concept that shifting the energy substrate preference away from fatty acid metabolism and toward glucose metabolism could be an effective adjunctive treatment in patients with HF

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Summary

Introduction

We have invited a few papers that address such issues and explain why despite the emergence of novel therapeutic approaches, that promise life prolongation and hospital length reduction, this patient population will still be needing rehospitalization and will often have a poor prognosis. Fukuta et al [8] on the prognostic value of left ventricular diastolic dysfunction in patients undergoing cardiac catheterization for coronary artery disease sheds light on this extremely important topic. E. Dardiotis et al [10], in a comprehensive review, underscore the importance for healthcare professionals to become familiar with assessment of cognitive performance using standardized screening instruments in their routine evaluations of HF patients.

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