Abstract
Background: Evaluation of patient reported outcome measures are important in improving the quality of life and effectiveness of care. Several measures have been developed to assess the health related quality of life of patients with tuberculosis. Objective: To systematically identify health related quality of life outcome measures that could be used in tuberculosis care and examine their feasibility of use and psychometric properties. A systematic literature review and analysis of psychometric properties. Method: Systematic literature research was done through PubMed, EMBASE and web search. Eligible studies assessed for unidimensional or multidimensional health related quality of life in patients with tuberculosis disease or infection using standardized instruments. Measuring psychometric properties such as internal consistency, reliability, validity and responsiveness were also examined. Results of included studies were summarized qualitatively. Results: From 6020 articles, 99 articles were selected for full text assessment. A total of 30 studies meet or inclusion exclusion criteria and examined the psychometric properties of 6 health related quality of life measures. Evidence was limited as half of the information on psychometric properties per instrument was missing and measurement error was not analyzed in any of the included articles and responsiveness was only analyzed in one study. Conclusion: A variety of instruments are used to assess the health related quality of life in tuberculosis patients. However, there has been only one disease specific instrument developed, making it difficult to understand the impact of illness. Most of the studies included does not required measuring properties or had problem with methodological quality. Further validation studies are required to support the use of health related quality of life measures in tuberculosis patients.
Highlights
Tuberculosis (TB) is a major disease infected approximately 10.4 million new cases in the world with 1.4 million deaths reported in the year 2015 [1]
We aimed to evaluate the most frequently used health related quality of life (HRQOL) instrument(s) in the patients of TB to demonstrate the properties and general recovery patterns based upon the Consensus-Based Standards for the assortment of health status measurement instruments (COSMIN) checklist [8]
30 articles were selected for review that measured the HRQOL in patients with TB in general and six studies with the aim to validate a HRQOL instrument in patients with TB
Summary
Tuberculosis (TB) is a major disease infected approximately 10.4 million new cases in the world with 1.4 million deaths reported in the year 2015 [1]. Several measures have been developed to assess the health related quality of life of patients with tuberculosis. Objective: To systematically identify health related quality of life outcome measures that could be used in tuberculosis care and examine their feasibility of use and psychometric properties. Eligible studies assessed for unidimensional or multidimensional health related quality of life in patients with tuberculosis disease or infection using standardized instruments. Measuring psychometric properties such as internal consistency, reliability, validity and responsiveness were examined. Further validation studies are required to support the use of health related quality of life measures in tuberculosis patients.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
