Abstract

Histamine is a bioactive nitrogenous organic compound of the family of monoamines produced by the action of enzymes in human and animal dung by fecal bacteria on protein materials, particularly the essential amino acid histidine. This type of material is also secreted in abundance in the body by cells known as mast cells circulating in the connective tissues, and also by white blood cells known as basophils, basal white blood cells, during allergic reactions and serious and life-threatening anaphylactic shock called anaphylactic shock (and during various allergic diseases). Mast cells are abundantly present in lung tissue, nasal mucosa, eye mucosal tissue, subcutaneous and between various mucosal tissues. In addition to what was mentioned above about the characteristics and functional role of histamine in the body, it has many harms as a result of its high level secretion as a result of a specific functional disorder or microbial invasion, as well as as a result of immune sensitivity, and damages are noted in the respiratory, digestive, immune and nervous systems.

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