Abstract
The article summarizes and supplements the results of the development of methods and tools for improving the reliability of differential measurement of local changes in electrical conductivity in electrolyte solutions using a pair of interdigitated transducers, which are used in conductometric biosensors. The aim of the work is a deeper suppression of the error due to the influence of background changes in a solution when the parameters of a pair of transducers are not completely identical. The essence of the issue, the causes and mechanism of the resulting error, and possible ways to reduce it are considered. The structure and algorithms of operation of a computer biosensor system with an intelligent module of a differential conductometric channel based on an alternating current bridge, with balancing in absolute value and phase of the disequilibrium signal, are described. Methods have been developed for tuning such a bridge to a special quasi- equilibrium state, in which a change in the background electrical conductivity does not change its output informative signal. The results of experimental studies are presented.
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