Hand posture modulates cortical finger representation in SII

Abstract

Somatosensory magnetic fields evoked by electrical stimuli of the thumb or the index finger were recorded using a whole head magnetoencephalography (MEG) system in 10 subjects performing different finger postures, open hand posture and close hand posture for picking up a small object. The mean Euclidean distances between the ECD (equivalent current dipole) locations for the thumb and index finger in the secondary somatosensory cortex (SII) across the subjects were 8.5 ± 2.1 mm in the close hand posture and 11.2 ± 2.6 mm in the open hand posture. The distance was significantly shorter in the close hand posture (paired t test, P = 0.002, n = 8). However, the distances of the P38m and P60m components in the primary somatosensory cortex (SI) were not significantly different between the two hand postures (P38m: 13.4 ± 5.6 mm in the open and 13.5 ± 3.9 mm in the close; P60m: 12.4 ± 2.6 mm in the open and 16.2 ± 5.3 mm in the close). This shortening of the spatial distance between the cortical finger representations suggests a similarity in humans of the rapid changes in the dynamics of cortical circuits reported in animal studies. In addition, the overlap of the cortical finger representations, which might be suggested by the shortening of the distance between the ECDs in SII, is likely to play a role in information integration between sensory inputs from the thumb and index finger.