Abstract

Hair Growth Defects of Diabetic and Hypercholesterolemic Wistar Albino Rats and Amelioration of Fish Oil-Treatment

Highlights

  • The hair shaft is a highly keratinized tissue outgrowth from the hair follicle

  • Increased deformity of hair shaft was detected in combined diabetes and hypercholesterolemia where thinning appeared and ruptured

  • Diabetes and or hypercholesterolemia interfered with hair shaft growth causing apparent reduction and deformation especially in diabetic and hypercholesterolemic group

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Summary

Introduction

The hair shaft is a highly keratinized tissue outgrowth from the hair follicle. It is formed of cortex and medulla. Little of studies are concerned with the effects of diabetes and or hypercholesterolemia in skin and hair follicle growth. Obesity and diabetes are considered chronic inflammatory diseases, largely due to the inflammatory cells in white adipose tissue including macrophages [3], B cells [4] and eosinophils [5]. These cells may interact directly through cell-cell contact, directly by releasing cell mediators within adipose tissue. Alopecia areata is one of the hair disease affected by the depletion of Submission: 28 July 2015 Accepted: 17 August 2015 Published: 21 August 2015

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