Abstract
ANTI-DIABETIC EFFECTS OF ETHANOL LEAF EXTRACT OF ONIONS (Allium cepa) ON ALLOXAN-INDUCED DIABETIC WISTAR ALBINO RATS
Highlights
Diabetes Mellitus (DM) is a group of metabolic disorders associated with disturbances in the metabolism of fuel molecules due to absolute deficiency of insulin, insufficient insulin secretion and / or its secretion [1]
Diabetes is a chronic disease characterised by high blood glucose level and abnormal metabolism of carbohydrates, protein and fat
The findings from this study indicate that the crude extract of Allium cepa leaf caused a significant hypoglycaemic and hypocholesterolemic activity in alloxan-induced diabetic rats validates its use in ethno – medicine for the control of diabetes mellitus
Summary
Diabetes Mellitus (DM) is a group of metabolic disorders associated with disturbances in the metabolism of fuel molecules due to absolute deficiency of insulin, insufficient insulin secretion and / or its secretion [1]. People cannot live without insulin [2] It is a widespread endocrine disorder that is associated with considerable morbidity and mortality and is found in all population throughout the world [3]. Herbal medicine and plant components with insignificant toxicity and less or no side effect are notable therapeutic options for the treatment of this disease around the world [4]. The most common herbal active ingredients used in treating diabetes are flavonoids, tannins, phenols and alkaloids [5]. The existence of these compounds implies the importance of the anti-diabetic properties of these plants [4]
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