Haematopoietic bone marrow and bony trabeculae: An uncommon mesodermal derivative in mature teratoma in a 14 year old girl

Abstract

Teratomas are embryonal tumours that emerge when totipotent germ cells evade the primary organisers' control over their growth and give rise to tumours that contain tissue from all three germ layers. They are cystic or solid, with mature or immature components. Histologically, teratomas are classified as mature (benign in 95% of cases) and immature with malignant transformation. They are rare tumours with a frequency of 1 in 10,000 births. Teratomas are located more often in the sacrococcygeal region, and in the ovary, the cervical localization represents 1.5% to 5% of all the localizations. They predominate among females. Mesodermal derivatives are relatively rare, and solitary organic development, especially of a mesodermal derivation in a random teratoma, is unique and crucial to distinguish for clinical reasons. Here, we present a 14-year-old female who presented with a submental swelling that, on histopathology, was diagnosed as a mature teratoma with hemopoietic tissue and bony trabeculae.