Dermatopathological diagnosis of porphyria cutanea tarda - Two case reports

Abstract

Porphyria cutanea tarda and its relationship with HIV and Hepatitis C are highlighted in the case reports. Porphyria cutanea tarda arises from a deficiency in the uroporphyrinogen decarboxylase enzyme, where there is an anomaly in the buildup of specific porphyrins, notably in blood vessels, liver, and skin. It can be either hereditary or acquired. In this context, we have discussed two individual patients with HIV and Hepatitis C who were diagnosed with porphyria cutanea tarda through skin biopsy.