Abstract

Abstract | During an outbreak of Foot and Mouth Disease (FMD) blood samples were collected from clinically dis-eased (n=10) and healthy (n=10) cattle and analysed for various hemato-biochemical parameters. Results indicated a significant increase in packed cell volume (PCV) (28.6 ± 0.98%, P= 0.036), lymphocytes (70.2 ± 6.20%, P= 0.0132), monocytes (8.2 ± 1.08%, P= 0.0132) and serum glucose (104.2 ± 15.59 mg/dL, P= 0.0053) whereas a significant de-crease in the concentration of hemoglobin (7.17 ± 0.07 gm/dL, P= 0.0004), basophils (0.3 ± 0.16%, P= 0.0241), eosino-phils (16.5 ± 1.83%, P= 0.0097), calcium (8 ± 0.41 mg/dL, P= 0.0125) and total protein (6.2 ± 0.19 mg/dL, P= 0.0058) was recorded in FMD infected cattle. Non-significant (>0.05) difference was noted between healthy and FMD P infected animals with respect to total erythrocyte count (TEC) (P= 0.6066), total leukocyte count (TLC) ( P= 0.3169), neutrophils ( P= 0.2358) and serum inorganic phosphorous ( P= 0.2507). It was concluded that FMD had major impact on hemato-biochemical profile of affected animals.

Highlights

  • Results indicated a significant increase in packed cell volume (PCV) (28.6 ± 0.98%, P=0.036), lymphocytes (70.2 ± 6.20%, P=0.0132), monocytes (8.2 ± 1.08%, P=0.0132) and serum glucose (104.2 ± 15.59 mg/dL, P=0.0053) whereas a significant decrease in the concentration of hemoglobin (7.17 ± 0.07 gm/dL, P=0.0004), basophils (0.3 ± 0.16%, P=0.0241), eosinophils (16.5 ± 1.83%, P=0.0097), calcium (8 ± 0.41 mg/dL, P=0.0125) and total protein (6.2 ± 0.19 mg/dL, P=0.0058) was recorded in Foot and Mouth Disease (FMD) infected cattle

  • Foot and Mouth Disease (FMD) is a highly communicable viral disease concerned primarily with cloven hoofed animals, caused by RNA viruses of the family Picornaviridae belonging to genus Aphthovirus (Belsham, 1993)

  • Mortality in adult animals due to FMDV infection is rare, but other defects associated with FMD are weight loss, decreased milk production and loss of draft power (Blacksell et al, 2008), while treatment cost and time spent caring for sick animals, the farmer has to face considerable losses (Rushton et al, 2002)

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Summary

Journal of Infection and Molecular Biology

Haemato-Biochemical Aspects of Foot and Mouth Disease in Cattle in Chittagong, Bangladesh. Abstract | During an outbreak of Foot and Mouth Disease (FMD) blood samples were collected from clinically diseased (n=10) and healthy (n=10) cattle and analysed for various hemato-biochemical parameters. FMD serotype A and O viruses, responsible for an outbreak in Southeast Asia, are endemic in this region (Rweyemamu et al, 2008b). Mortality in adult animals due to FMDV infection is rare, but other defects associated with FMD are weight loss, decreased milk production and loss of draft power (Blacksell et al, 2008), while treatment cost and time spent caring for sick animals, the farmer has to face considerable losses (Rushton et al, 2002). The international trade of animal products is constrained by FMD. Due to the infection of FMDV, the livestock industry faces severe economic losses by mortality in young animals and morbidity in adult.

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