Abstract
The study was conducted in six crossbred female cattle aged nine months to five years and weighing between 82-375 kg, to evaluate haematobiochemical and blood gas changes in during multimodal general anaesthesia. The animals were premedicated by intravenous administration of butorphanol (0.05mg/kg body weight) immediately followed by xylazine (0.02 mg/kg body weight). On achieving sedation, the animals were controlled in left lateral recumbency and induction of anaesthesia was carried out by intravenous administration of ketamine and midazolam at the dose rate of 4.0 and 0.2 mg/kg body weight respectively. Endotracheal intubation was performed and maintenance of general anaesthesia was carried out using isoflurane in 100% oxygen. The variation in total erythrocyte count, total leukocyte count, volume of packed red cells, platelet count and haemoglobin were non-significant before and after anaesthesia. A non-significant lymphocytopaenia with neutrophilia and mild variations in aspartate aminotransferase and alanine aminotransferase enzyme levels were also noticed. Blood pH reduced significantly (p<0.05) after induction of anaesthesia and returned to baseline values after recovery whereas PvCO2 (p<0.05) and base excess (p<0.01) values increased significantly after induction of anaesthesia. The blood bicarbonate did not alter significantly following induction of anaesthesia.
Highlights
The study was conducted in six crossbred female cattle aged nine months to five years and weighing between 82-375 kg, to evaluate haematobiochemical and blood gas changes in during multimodal general anaesthesia
A short acting benzodiazepine, when administered with ketamine reported to result in better muscle relaxation and analgesia than xylazine with less cardiopulmonary side effects in clinical setting
Six crossbred female cattle aged nine months to five years with body weight ranging from 82-375 kg were subjected to elective surgical procedures
Summary
The study was conducted in six crossbred female cattle aged nine months to five years and weighing between 82-375 kg, to evaluate haematobiochemical and blood gas changes in during multimodal general anaesthesia. The mean total leukocyte count (103/ μL) among animals decreased non-significantly after recovery than that before anaesthesia and was 17.75 ± 2.98 and 17.02 ± 2.73 respectively (Table 1). The decrease in haematocrit, platelet count and haemoglobin values observed on recovery from anaesthesia was not significant when compared to pre surgical values.
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