Abstract

Calcium oxalate crystals were precipitated using reverse osmosis in a hollow fibre system to produce supersaturation in both the absence and in the presence of various additives. Significant changes in the particle size distribution produced were detected when precipitation was carried out in the presence of pyrophosphate, glutamic acid, citric acid and heparin. Magnesium was effective when added in relatively high concentrations. Calcium oxalate dihydrate was the main crystallographic form produced but in the presence of glutamic acid and magnesium the monohydrate and the trihydrate respectively were detected. SEM photographs indicate that significant habit modification occurs in the presence of some of these additives.

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