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Open Accesshttps://doi.org/10.1016/j.jacc.2017.07.644
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Cite Publication Date: Oct 1, 2017 | |
 License type: publisher-specific-oa |
Endothelin-1 (ET-1) is up-regulated in astrocytes under ischemia. Our previous studies suggest that astrocytic ET-1 has deleterious effects on water homeostasis, cerebral edema and BBB integrity, which contribute to more severe ischemic brain injury. We also found that astrocytic ET-1 plays a
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