Abstract
To amend the autistic behavior in prenatally exposed valproic acid (VPA) bytreatment with probiotic supplementation.Methods: autism induced by administration of VPA 300mg/kg, i.p. on gestation 12.5and 13 days. The offspring were weaned on postnatal (PND) day 23; separate them intosix groups, each group with six rats. I) Control group II) Autistic group III) B. Infantis (5billion cfu/gm p.o); IV) B. longum (5 billion cfu/gm, p.o); V) L. Plantarum (5 billioncfu/gm, p.o) VI) L. Bulgaricus (5 billion cfu/gm, p.o) treat the animals with probiotics onPND 23 – PND 50. Behavioral studies are performed on various postnatal days untilPND 50.Results: supplementation with probiotics PND 23 - 50 showed that there is a significantrecovery in behavioral activity in comparison to Autistic group.Conclusion: Results of our study revealed that Probiotics can influence the braindevelopment and behavior. It might be through communication between gut and brain.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callSimilar Papers
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
