Abstract

Diabetes mellitus (DM), an endocrine disorder, epidemic all over the world which causes dysfunction of reproductive capacity. Gum Arabic (GA), a dietary fibre has potential health effects on reproductive system

Highlights

  • Bioactive natural principles are reported used as a source of medicinal agents for several decades [1,2]

  • Treatment of Gum Arabic (GA) significantly (P

  • Testis of diabetic rats showed obvious degeneration whereas; slight degeneration was seen in GA treated rats compared to control

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Summary

Introduction

Bioactive natural principles are reported used as a source of medicinal agents for several decades [1,2]. The chronic hyperglycemia in diabetes patients is reported to be associated with long-term tissue damage [18], dysfunction [18], and failure of various organs [19], in particular the reproductive organs [20]. Hyperglycaemia trigger reactive oxygen species production [27], which in turn causes cell damage via different mechanisms [28,29,30]. Both tissues and cellular damage consequences in the secondary complications of DM [31]

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