Abstract

At the moment we have three different consensus from three different Scientific Societies with guidelines for insulinization. According to the SED (Spanish Diabetes Society), with HbA1c between 6,5–8,5%, it is recommended to beguin with life style changes + metformine and when not enough add a second oral drug or insuline. With HbA1c > 8,5% it is recommended to beguin with metformine + insuline.According to the ADA (American Diabetes Association) and EASD (European Association for the Study of Diabetes) consensus, there are three steps to be followed when insulinization: life style changes, add second oral drug or insuline and beguin with insuline or intensify it.The AACE/ACE guide (American Association of Clinical Endocrinologists/American College of Endocrinology) is the most conservative guide when adding oral drugs, using insuline only when several oral drugs combinations have failured and avoiding the sulfonylureas or glinidas use with insuline.

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