Group-specific component (Gc) polymorphism in Japanese: an investigation on the phenotypic distribution with regard to the Gc allele.

Abstract

Using the prolonged immunoelectrophoresis, Gc determination was performed in 1,347 plasma collected from 3 local populations in Japan. Six phenotypes determined by the codominant alleles,Gc1,Gc2 andGcJ, were observed, in which a new phenotype GcJ-J was included. This study revealed the presence of at least 3 polymorphic alleles at Gc locus in Japanese population.