Abstract
Nanoparticles (NPs) have unique properties compared to their bulk counterparts, and they have potentials for various applications in many fields of life science. Green-synthesized NPs have garnered considerable interest due to their inherent features such as rapidity, eco-friendliness and cost-effectiveness. Zinc oxide nanoparticles (ZnO NPs) were synthesized using an aqueous extract of Kalanchoe blossfeldiana as a reducing agent. The resulting nanoparticles were characterized via X-ray diffraction (XRD), dynamic light scattering (DLS), UV-Vis spectroscopy, photoluminescence (PL), transmission electron microscopy (TEM), scanning electron microscopy (SEM) and energy-dispersive spectroscopy (EDS). The antimicrobial potential of the synthesized ZnO NPs against bacterial and fungal strains was examined by the disk diffusion method, and they showed a promising antibacterial and antifungal potential. The catalytic activity of the synthesized ZnO NPs in reducing methylene blue (MB) and eosin was studied via UV-Vis spectroscopy. The decolorization percentages of the MB and Eosin Y dyes were 84% and 94%, respectively, which indicate an efficient degradation of the ZnO NPs. In addition, the cytotoxic activity of the ZnO NPs on the HeLa cell line was evaluated via in vitro assay. The MTT assay results demonstrate a potent cytotoxic effect of the ZnO NPs against the HeLa cancer cell line.
Highlights
Nanotechnology is one of the fastest-growing technologies, which will likely form the basis of multiple technological and biotechnological innovations; it is considered as the upcoming industrial revolution of the century [1]
This paper reports the green synthesis of Zinc oxide nanoparticles (ZnO NPs) from an aqueous extract of K. blossfeldiana and zinc nitrate hexahydrate as the Zn precursor
The results show that the treatment with the ZnO NPs significantly inhibited the growth of cells (p ≤ 0.05) and the reduction was concentration dependent
Summary
Nanotechnology is one of the fastest-growing technologies, which will likely form the basis of multiple technological and biotechnological innovations; it is considered as the upcoming industrial revolution of the century [1]. Molecules 2020, 25, 4198 industrial fields, including chemistry, biology, medicine and physics [2,3,4]. Owing to their superior physicochemical and biological properties over the bulk materials, nanomaterials have significant potential in different fields of science [5]. The size of nanoparticles (NPs) (1–100 nm) offers a higher surface-to-volume ratio, which results in high surface reactivity [6,7]. The reaction of a salt or ligand has broadened the spectra of many biological and environmental research areas and plays a significant role in electronic devices, radiolabeling, medicinal applications and contaminant detection [13]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
