Abstract
Mixed metal oxides (CuO, ZnO, and MnO) nanoparticles (NPs) were synthesized by the green process which is simple, cost-effective, eco-friendly, and non-toxic. In the green synthesis method, rose petals extracts were used as a reducing and capping agent while salt solutions (CuCl2, MnCl2, and ZnSO4) were used as a precursor that lead to the formation of mixed metal oxides (CuO, ZnO, MnO) NPs. UV-Visible and FTIR spectroscopy were used for the analysis of mixed metal oxides (CuO, ZnO, MnO) NPs, which showed maximum absorbance in the range of 280 to 370 nm. The presence of particular peaks in FTIR verified the synthesis of mixed metal oxide nanoparticles. The antimicrobial and antifungal activities of mixed metal oxides (CuO, ZnO, MnO) NPs were carried out by the disc diffusion method and well diffusion method. Mixed metal oxides (CuO, ZnO, MnO) NPs showed antimicrobial activity against Escherichia coli and antifungal activity against Candida albicans, Curvularia lunata, Aspergillus niger, and Trichophyton simii. So, these mixed metal oxides (CuO, ZnO, MnO) NPs can be effective in the pharmaceutical sector.
 Keywords: antifungal, antimicrobial, green synthesis, mixed metal oxides nanoparticles (MONPs), rose petals extracts
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