Abstract
The fabrication of metal nanoparticles through green synthetic pathways using plant extracts has increased attention due to low cost, benevolent methods, fewer hazardous byproducts, and applications. Silver nanoparticles (AgNPs) were synthesized by reacting to aqueous root extracts of Rubus ellipticus Sm. (RERE) with AgNO3 solution (1 mM) at an ambient condition. The visual change of color from light yellow to reddish brown and the absorption peak at 416‐420 nm in the UV‐visible spectra indicated the formation of AgNPs in the solution. The shifting of the positions in the FTIR spectra indicated the potential role of the functional groups as capping and stabilizing agents. The powder XRD diffractogram exposed the crystalline nature of the nanoparticles. The surface morphology and the elemental composition of the AgNPs were established by the FESEM and EDX analysis. The TEM images revealed the spherical and monodispersed nanoparticles of size ranging from 13.85 to 34.30 nm with an average of 25.20 ± 7.01 nm (n = 10). The biogenic AgNPs showed a better 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) radical scavenging activity with lower IC50 (13.83 ± 0.33 μg/mL) as compared to that of the RERE with IC50 (15.86 ± 4.14 μg/mL). The synthesized AgNPs showed higher zones of inhibition (ZOI) on the agar well diffusion method against Enterococcus faecalis (ATCC 29212), Escherichia coli (ATCC 25922), Staphylococcus aureus (ATCC 25923), and Klebsiella pneumoniae (ATCC 700603). The result of this study highlights the potential benefits of R. ellipticus root extract‐based AgNPs for biomedical practices.
Highlights
Nanotechnology is emerging as an extensive interdisciplinary area of research all over the world for a few decades
We have reported the abundance of these phytochemicals in the roots of R. ellipticus collected from the same site [24]
We found that our AgNPs showed greater activity against the Gram-negative (E. coli and K. pneumoniae) than Gram-positive (E. faecalis and S. aureus) bacteria
Summary
Nanotechnology is emerging as an extensive interdisciplinary area of research all over the world for a few decades. The design, manufacturing, characterization, and application of nanoparticles have increased attention due to their unique physical and chemical properties [1]. Nanoparticles are extremely small particles with their size ranging from 1 to 100 nm and exhibit completely new properties compared to that of bulk materials. They have a higher surface area to volume ratio, which brings the variation in the other specific parameters like size, distribution, and morphology. The higher surface area of the AgNPs is responsible for their increased catalytic and biological properties [2]. The nanoparticles of noble metals like gold, silver, palladium, and platinum are extensively used in various industrial and pharmaceutical practices due to their incredible physicochemical, optical, and biological properties [3]
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call