Green synthesis of gold nanoparticles obtained from Punica granatum flower extract for phytochemical determination and antibacterial activity

Abstract

Numerous biomedical applications such as biological detection, drug delivery, diagnostic imaging and tissue engineering, have incorporated nanotechnology. Parts of the pomegranate (Punica granatum) flower are known to have strong antibacterial properties. In this study, the anti-susceptibility test was used to look into the green synthesis of gold nanoparticles using Punica granatum and the inhibitory effect of these particles. According to the current study, prepared AuNPs were evaluated using a variety of methods including UV-visible spectrophotometry, FTIR, SEM and GC-MS to identify the phytochemicals. The bacterial and fungal species Candida albicans and Malassezia furfur that are inhibited by the synthetic colloidal gold nanoparticles made with Punica granatum flower extract include Escherichia coli, Pseudomonas, Staphylococcus, Klebsiella pneumoniae and Protea. In this work, we describe a simple, quick and reproducible method for the environmentally friendly synthesis of AuNPs without the need for expensive reducing agents. Simple incubation of a flower extract with aqueous gold ions at ambient temperature resulted in ‘medium monodisperse’ nanoparticles, suggesting that the plant extract acted as a strong reducing agent.