Abstract
This study looked into the high yield production of new spiropyrrolooxindole derivatives. In order to create these new compounds, a multicomponent reaction involving isatin, malononitrile, alkyl 2,4-dioxo-4-(arylamino) butanoate derivatives, primary amines, and ethyl bromopyruvate was carried out in water at room temperature with catalytic amounts of Ag@KF/CP NPs acting as a high performance catalyst. The antioxidant property of new synthesized spiropyrrolooxindoles are owing to having NH group which was evaluated by two procedures. Also, the antimicrobial activity of new generated spiro isatins was evaluated by disk distribution process utilizing two kinds of Gram-negative bacteria and Gram-positive bacteria; proving bacterial growth was stopped by using of these compounds. Also, the catalytic activity of the green synthesized Ag@KF/CP NPs was evaluated in the reduction of organic pollutants such as 4-nitrophenol (4-NP) in water at mild conditions. The results indicated that the biosynthesized NCs have very high and effective catalytic activity for organic pollutants within few seconds. Applied to the preparation of spiropyrrolooxindole derivatives, this method has short reaction times, high product yields, and the ability to separate catalyst and product using simple procedures.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.