Green Route Synthesis of Bio-active Cd(II) and Hg(II) Complexes With ‘N’ Donor Novel Schiff base and Oxalate ion

Abstract

Green route synthesis of bio-active diamagnetic Cd(II) and Hg(II) complexes with Schiff base and oxalate ion were synthesized using water as a solvent and characterized by using electronic spectra (UV-visible), Fourier transforms infrared (FT-IR), 1H and 13C-NMR spectroscopy, mass spectra and physical characterization such as CHN analysis, metal estimation and molar conductivity. 1H- and 13C-NMR spectra of ligand complex compared with Schiff base. The complexes have the general formula of ML2X (M= Cd(II) & Hg(II), L-C15H13N, X-C2O4 ) confirmed based on the results of elemental analysis, metal estimation and the reasonable shift of mass spectra, FT-IR and NMR spectral signals of the complexes compared with free Schiff base. The coordination of Schiff-base and anionic ligands through an inner-sphere coordination mode by imine nitrogen and the oxygen atom of oxalate ion. The conductivity measurements of metal complexes indicate that they are non-electrolyte. The Schiff base and its metal chelates were tested in-vitro bio-potential activity against bacterial strain such as E. coli, S. aureus, B. subtilis, P. aeruginosa and fungal strain viz., C Albicans, A. Niger by Agar disc diffusion method using chloramphenicol and fluconazole as bacterial and fungal standard. The results revealed that the metal (II) chelates exhibited higher antibacterial activity than the free Schiff base.