Abstract
As the potential risks on human and aquatic animal exposed to the glucocorticoids in environment, it is essential to detect anti-epidemic pharmaceutical in real water samples. In this work, a core-shell shape, magnetic suspension particle sorbents of Fe3O4@oleic acid@polydopamine (Fe3O4@OA@PDA) were synthesized for magnetic dispersive solid phase microextraction (MDSPME), which possessed considerable dispersibility in water samples and extracted three glucocorticoids through hydrogen bonding with high detection sensitivity. The adsorption process of MDSPME was investigated by thermodynamic and kinetic theory, which demonstrated that the kinetic processes of adsorption were in accordance with the quasi second order kinetic model, and the adsorption isotherm was in accordance with the Freundich model. Combined with high performance liquid chromatography-Ultraviolet spectrophotometer detector, the proposed method had a linear range of 5–200 μg/L with an ultra-low detection limit down to 0.5–1.1 μg/L. The Green Analytical Greenness Metric (AGREE) software was employed to evaluate the greenness of the analytical method. This work presented an effective strategy for creating ultrasensitive and cost-effective probe for detection in anti-epidemic drugs.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
