Abstract
An efficient and mild synthesis of some diverse iminosaccharides of pyrazole has been carried out. Compounds (8a-b) have been synthesized by the treatment of isoniazide with chalcones (6a-b) using [bbim][BF 4 ] ionic liquid as a solvent under microwave irradiation. Compounds (8a-b) on reaction with various aldoses afforded corresponding iminosaccharides compounds containing pyrazole moiety (9a-l) in presence of ionic liquid under microwaves. The products have been isolated, purified and characterized by different spectral methods i.e. IR, 1 H NMR, 13 C NMR and Mass spectra. The potent antimicrobial effects (MIC) of the synthesized compounds were investigated.
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