Abstract
Sarcoidosis is an idiopathic inflammatory disease characterized by granuloma formation in various tissues, most commonly the lungs, lymphatics, skin and eyes. Involvement of the breast in sarcoidosis is rare, and can be defined into three subsets, including granulomas localized to the breast, referred to as breast sarcoidosis. Breast sarcoidosis may present with systemic findings such as erythema nodosum, arthritis, and uveitis, and unlike typical sarcoidosis, commonly manifests during pregnancy. In this report, we present a rare case of breast sarcoidosis presenting in a pregnant female with associated erythema nodosum, arthralgias and ocular complaints.
Highlights
Sarcoidosis is an idiopathic inflammatory disease characterized by granuloma formation in various tissues, most commonly the lungs, lymphatics, skin and eyes
The patient was diagnosed with sarcoidosis with a presentation of erythema nodosum, arthralgias, granulomatous mastitis and ocular complaints
Treatment with prednisone 20 mg daily resulted in complete resolution of erythema nodosum lesions, ocular complaints, and arthralgias, and significant reduction in the breast mass
Summary
Sarcoidosis is an idiopathic inflammatory disease characterized by granuloma formation in various tissues, most commonly the lungs, lymphatics, skin and eyes. A 31-year-old African-American woman, G3P2002, presented 26 weeks pregnant to her Obstetrician with a painful, red tumor in her right breast. She had a 5 x 13 cm indurated mass in her right breast with associated tender, rubbery lymphadenopathy in the right axilla, (Fig. 1) as well as red tender subcutaneous nodules on her anterior legs (Fig. 2) and forearms.
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