Abstract
Granulomas in gastric biopsy specimens are extremely rare, and in developed countries, more than half are associated with different causes such as Crohn's disease, sarcoidosis and Wegener's granulomatosis. The diagnosis of isolated granulomatous gastritis is established only after exclusion of other organic granulomatous disease. We report six cases of granulomatous gastritis. Five were positive for Helicobacter pylori. No other causes of granulomatous gastritis could be found. In one case an isolated granulomatous gastritis was diagnosed. The granulomas were mainly found in the antrum and corpus. The final diagnosis of granulomatous gastritis is based on morphological findings and clinical and laboratory data. Because of the high incidence of Helicobacter pylori detected in granulomatous gastritis, Helicobacter pylori can be causal in its pathogenesis.
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