Abstract
Grand challenges in stem cell treatments.
Highlights
Stem cells mainly include embryonic stem cells (ESC), pluripotent stem cells, Epiblast-derived stem cells (Epi-SC), and adult tissue stem cells
There are ethical issues when using human embryos, and ESC transplants into mouse models can result in malignant tumors
Human ESC lines derived from single blastomeres have been reported (Klimanskaya et al, 2006)
Summary
Stem cells mainly include embryonic stem cells (ESC), pluripotent stem cells (iPS), Epiblast-derived stem cells (Epi-SC), and adult tissue stem cells. There are ethical issues when using human embryos, and ESC transplants into mouse models can result in malignant tumors. Further challenges facing research in the use of ESC are how to reduce contamination, and prevent cancer risk.
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