Abstract

During post-transplant evolution, adolescents may present problems with adherence to treatment, becoming a high-risk group for graft loss. Here, we report a case which describes an adolescent patient who lost a graft due to humoral rejection associated with lack of adherence to treatment. During chronic peritoneal dialysis therapy, the patient developed pain and increased volume in the graft area, fever, gross hematuria and leukocyturia upon urine examination. The patient was diagnosed with graft immune intolerance syndrome and transplantectomy was suggested. Finally, a graft embolization was performed. A decrease in symptoms was observed until the patient became asymptomatic.

Highlights

  • Renal transplantation is the ideal treatment for adolescents with chronic kidney failure

  • The patient was diagnosed with graft immune intolerance syndrome and transplantectomy was suggested

  • Graft intolerance is a syndrome characterized by enlargement of the graft, hematuria, signs of acute inflammation, anemia with resistance to erythropoietin, fever, malaise, raised C-reactive protein

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Summary

Introduction

Renal transplantation is the ideal treatment for adolescents with chronic kidney failure. During the post-transplant evolution, adolescents may present problems with adherence to treatment, becoming a high-risk group for graft loss. Graft intolerance is a syndrome characterized by enlargement of the graft, hematuria, signs of acute inflammation, anemia with resistance to erythropoietin, fever, malaise, raised C-reactive protein. There are no cases reported in children with this syndrome and with surgical treatment of embolization. We believe that it is important to report this case about a girl who lost the graft

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