Graft Failure After Penetrating Keratoplasty in Eyes With Ahmed Valves

Abstract

We read with interest the recently published article “Graft Failure after Penetrating Keratoplasty in Eyes with Ahmed Valves,” by Hollander and associates. 1 Hollander D.A. Giaconi J.A. Holland G.N. et al. Graft failure after penetrating keratoplasty in eyes with Ahmed Valves. Am J Ophthalmol. 2010; 150: 169-178 Abstract Full Text Full Text PDF PubMed Scopus (43) Google Scholar They concluded that corneal graft failure in eyes with Ahmed valves (AVs) was high. They also report that poor intraocular pressure control may be related to graft failure. They found the strongest risk factors for graft failure in this population was a history of previous failed penetrating keratoplasty (PK) and corneal stromal neovascularization, whereas the use of glaucoma medication and a lower intraocular pressure was associated with a significantly decreased risk of graft rejection. We have a few concerns. Graft Failure After Penetrating Keratoplasty in Eyes With Ahmed ValvesAmerican Journal of OphthalmologyVol. 150Issue 2PreviewTo determine incidence and risk factors for graft failure following penetrating keratoplasty (PK) in eyes with Ahmed valves (AV). Full-Text PDF ReplyAmerican Journal of OphthalmologyVol. 151Issue 2PreviewWe appreciate the interest expressed in our article1 by Patel and associates. The fact that they have concerns about our study indicates a need for clarification. Our objectives were to describe outcomes associated with penetrating keratoplasty (PK) in eyes that had previously undergone placement of an Ahmed valve (AV); to determine the incidence of graft failure in such eyes; and, because not every patient experiences graft failure, to identify risk factors other than the presence of an AV that also contribute to graft failure in this population. Full-Text PDF