Abstract

Neutral gossypol solution injected peritoneally into NMRI mice preimplanted with Ehrlich ascites tumour cell, at a dose of 25–100 μg/mouse per day, lengthened the number of survival days of the hosts. This gossypol effect on tumour cell proliferation is concentration dependent. The optimum dose is 100 μg. However, at too high a dose, the gossypol caused a body weight loss and the death of the tumour-bearing mice.

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