Abstract
Objective To report on the treatment with recombinant FSH of an azoospermic normogonadotropic patient with a Y-chromosome microdeletion. Design Case report. Setting An assisted reproduction center. Patient(s) A 32-year-old patient with azoospermia. Intervention(s) Histological testicular biopsy, Y-chromosome screening, FSH treatment, and intracytoplasmic sperm injection. Main outcome measure(s) Fertilization, embryo development, pregnancy, and delivery. Result(s) After 6 months of treatment with gonadotropins, a small number of spermatozoa were found in the patient's ejaculate and used for IVF, resulting in a successful twin pregnancy and the delivery of two healthy girls. Conclusion(s) In this study, treatment with gonadotropins promoted the spermatogenesis process and led to the production of spermatozoa in a normogonadotropic azoospermic patient.
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