Abstract
Fabrication of gold coated silicon nanowires (AuSiNW) substrate is introduced in detail and A hybrid substrate is designed for surface-enhanced Raman spectroscopy (SERS). The SERS behaviors are discussed and compared by the detection of 4, 4’-Bipyridine. Gold nanoparicles is modified on the surface of AuSiNW to form the “hot gap”. Molecules captured in these “hot gap” can generate huge Raman signal. Double-fold enhancement of SERS signal has been achieved comparing with AuSiNW. The as-fabricated hybrid substrate exhibit high SERS sensitivity, long-term stability, and consistent reproducibility, highly potential for realizing a rapid, cost-effective, and label-free SERS-based biosensor.
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