Abstract
AbstractGraphene oxide is a flexible nanoscale building block, which is contributed to improve the electrical, optical, and chemical properties. Here, gold nanoparticles on graphene oxide substrate were synthesized as sensitive nanoprobes for rapid L‐cysteine detection. The smartphone‐based system with multimode analysis of red‐green‐blue (RGB), hue‐saturation‐value (HSV), hue‐saturation‐lightness (HSL), and cyan‐magenta‐yellow‐black (CMYK), were proposed for the investigation of interactions between the nanoprobes and L‐cysteine. Then, optical absorption spectra were further examined to confirm the concentration characteristics of L‐cysteine. Results suggested that gold nanoparticles on graphene oxide substrate had satisfying linearity and stability in dose‐dependent responses to L‐cysteine detection in the multimode analysis with the limit of detection at 0.06 μM. Therefore, the smartphone‐based nanoprobes system not only equipped with a high resolution camera and a powerful processor, but also was a fully automated device without additional label or complex detection. These features make it to be a convenient and efficient analysis platform for multiple fields, such as clinical application, industrial quality control, environment monitoring, and food assessment.
Published Version
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