Abstract
Parathyroid glands secrete the parathyroid hormone that plays an essential role in bone remodeling. Excessive production of parathyroid hormone causes a common metabolic bone disorder known as hyperparathyroidism that is classified into primary, secondary, or tertiary. In hyperparathyroidism, the late bony complication is manifested as a giant cell osteolytic lesion called “brown tumor.” Primary hyperparathyroidism is usually a sporadic disorder, but in minority of cases it occurs in inherited forms, and one of these forms is the hyperparathyroidism-jaw tumor syndrome, which is characterized by primary hyperparathyroidism and ossifying fibroma in the mandible and/or maxilla.
Highlights
Introduction ere are4 parathyroid glands located behind the thyroid gland which secrete parathyroid hormone “parathormone” (PTH) which maintains a proper calcium balance in bloodstream and in tissues that require calcium for their physiological functions
Association of primary hyperparathyroidism and ossifying fibroma of the jaw is seen in a rare hereditary syndrome referred as hyperparathyroidismjaw tumor (HPT-JT) [3]
Is review focuses on the gnathic metabolic bone changes that result from increased parathyroid hormone secretion in case of hyperparathyroidism
Summary
Introduction ere are4 parathyroid glands located behind the thyroid gland which secrete parathyroid hormone “parathormone” (PTH) which maintains a proper calcium balance in bloodstream and in tissues that require calcium for their physiological functions. Brown tumor is comparatively an uncommon non-neoplastic osteolytic lesion of bones that appears in advanced stage of hyperparathyroidism [2]. Association of primary hyperparathyroidism and ossifying fibroma of the jaw is seen in a rare hereditary syndrome referred as hyperparathyroidismjaw tumor (HPT-JT) [3].
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