Abstract
ABSTRACT Different levels of glycosaminoglycans (chondroitin sulfate and glucosamine sulfate) and vitamin C were injected in ovo to determine whether additive use influences the incubation parameters and bone characteristics of posthatch chicks. Hatchability was not affected by addition of glycosaminoglycans and vitamin C in ovo. However, chicks that received 4 μg additive showed 2.86% reduction in total mortality when compared with chicks from non-injected eggs. Moreover, tibia area and femur bone mineral density increased in chicks from eggs injected with [...]
Highlights
Upon reaching rapid body growth, efficient feed utilization, and maximum breast meat deposition, broilers begin to show disorders in their bone structure, with increased occurrence of angular and torsional deformities, tibial dyschondroplasia, rickets, osteochondrosis, and femoral necrosis (Almeida Paz et al, 2010)
Different levels of glycosaminoglycans and vitamin C were injected in ovo to determine whether additive use influences the incubation parameters and bone characteristics of posthatch chicks
In ovo feeding with chondroitin sulfate, glucosamine sulfate, and vitamin C was evaluated in terms of ability to promote changes in bone and cartilage development posthatch
Summary
Upon reaching rapid body growth, efficient feed utilization, and maximum breast meat deposition, broilers begin to show disorders in their bone structure, with increased occurrence of angular and torsional deformities, tibial dyschondroplasia, rickets, osteochondrosis, and femoral necrosis (Almeida Paz et al, 2010). Polysulfated glycosaminoglycans (GAG) such as glucosamine and chondroitin have anti-inflammatory action and are pharmacologically classified as slow-acting symptomatic drugs that reduce the symptoms of bone disorders such as osteoarthritis in humans and some animal species (Brandt et al, 2002). They stimulate the synthesis of proteoglycans and collagen, increasing the proliferation of chondrocytes and bone matrix biosynthesis (Altman et al, 1989; Clark, 1991). No research has been published regarding the use of GAG in ovo feeding or in the diet of broilers and laying hens
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