Abstract
The specific activity of the enzyme glyceraldehyde 3-phosphate dehydrogenase declines as a function of age. Immunotitration with monospecific antibodies demonstrated that with age there is an increase of catalytically defective, but antigenically reactive enzyme molecules in the lens. Antiserum, produced against denatured enzyme, removed the inactive molecules from lens homogenates, without effect on the levels of enzyme activity. These studies suggest that inactive enzyme molecules in agang lenses are totally devoid of catalytic activity, and are at least partially denatured.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
