Abstract
Objectives: Metabolic syndrome (MetS) is a cluster of several metabolic disorders including hyperglycemia, reduced high-density lipoprotein cholesterol, and raised triglyceride level in serum, hypertension, and abdominal obesity. Glycated hemoglobin (HbA1c) is used as one of the diagnostic criteria for diabetes and diagnostic tool for MetS.
 Methods: The present study was conducted at Prasad Institute of Medical Sciences. The study includes 150 patients with MetS as a case and 150 healthy volunteers as a control. MetS was diagnosed according to National Cholesterol Education Program’s Adult Treatment Panel III criteria. HbA1c was assayed in various components of MetS.
 Results: It was found that HbA1c was significantly higher in MetS patients when compared to control group.
 Conclusion: Our study suggests that HbA1c might be used as a diagnostic criterion for MetS. Therefore, proper glycemic control should be maintained by maintaining HbA1c level <6.5% to prevent from diabetes and MetS.
Highlights
Metabolic syndrome (MetS) is a clustering of hypertension, obesity, glucose intolerance, and dyslipidemia [1]
Several studies conducted in the Europe, China, and the USA have found that HbA1c may be used in place of fasting blood sugar (FBS) in identifying persons with MetS
A statistically highly significant difference was observed among two groups (p
Summary
Metabolic syndrome (MetS) is a clustering of hypertension, obesity, glucose intolerance, and dyslipidemia [1]. It is expected that about 20–25% of adult population have MetS and they are 2 times likely to die from MetS and 3 times as likely to have a stroke or heart attack compared with people without MetS [2]. It poses a rise in public health and clinical challenge worldwide in the wake of urbanization, increasing obesity, sedentary lifestyle habits, and surplus energy intake [3]. Study predicts the prevalence of MetS and compared FBS ≥5.6 mmol/L and HbA1c 5.6% as glycemic component of MetS [4]
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