Abstract
Glutamylcholine was administered in 158 cases of hypertension and the results presented below were obtained.1. There was a marked improvement in subjective symptoms and blood pressure.2. The capillary resistance which was at an average level of 26mm Hg prior to treatment, showed an average rise of 37mm Hg after treatment.3. The capillary configuration was examined. Following treatment, there was an acceleration of blood flow and dilation and elongation of the arterial loop.4. The blood picture showed little change.5. A slight decrease in viscosity of the serum was noted.6. There was no worsening in the eyegrounds during the period of treatment.7. Electrocardiographic examinations showed a large number with left ventricular changes and improvement was observed after treatment. There were no detrimental effects on the cardiac muscle.8. The pressure which once dropped to normal levels gradually rose again. This took place in the majority of cases in 2-4 weeks.9. Serum total protein, albumin and protein quotient were reduced and globulin slightly increased but a tendency to recovery appeared after 8 weeks of treatment.10. The total lipid level of the serum was in the upper limits of normal values and at 4 weeks of treatment, a further rise was apparent, but in 8 weeks a trend toward decrease was seen.11. Examination of the serum cholesterol showed that the free form was unchanged, whereas the total and esterified were increased, which however decreased following treatment.12. The serum chlorine content was increased, but in the cases in which GlC was definitely effective, there was a decrease following treatment.13. Serum sodium level rose, but fell following treatment, especially in cases which responded poorly.14. The serum potassium level rose, but fell following treatment and the calcium which was reduced, increased after treatment.15. Serum cholinesterase was increased, but following the administration of GlC, returned to normal levels.
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
