Abstract
Glutamate dehydrogenase catalyzes the reversible oxidative deamination of L-glutamate to α-ketoglutarate and ammonia with pyridine nucleotides as coenzyme Open image in new window The above reaction plays a key role in linking nitrogen metabolism to the tricarboxylic acid cycle (Fig. 1). Open image in new window Fig. 1 Role of glutamate dehydrogenase (1) in cellular metabolism. Circles: points of feedback control. (From. STADTMAN, 1966)
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