Abstract
BackgroundGlomus tumors are rare benign neoplasms that usually occur in the upper and lower extremities. Oral cavity involvement is exceptionally rare, with only a few cases reported to date.Case presentationA 24-year-old woman with complaints of swelling in the left floor of her mouth for 6 months was referred to our institution. Her swallowing function was slightly affected; however, she did not have pain or tongue paralysis. Enhanced computed tomography revealed a 2.8 × 1.8 × 2.1 cm-sized well-defined, solid, heterogeneous nodule above the mylohyoid muscle. The mandible appeared to be uninvolved. The patient underwent surgery via an intraoral approach; histopathological examination revealed a glomus tumor. The patient has had no evidence of recurrence over 4 years of follow-up.ConclusionsGlomus tumors should be considered when patients present with painless nodules in the floor of the mouth.
Highlights
Glomus tumors are rare benign neoplasms that usually occur in the upper and lower extremities
Glomus tumors should be considered when patients present with painless nodules in the floor of the mouth
Glomus tumors account for only 1.6% of all soft tissue tumors and typically present as blue-red nodules that occur in the deep dermis or subcutis region [2]
Summary
The glomus body is a special arteriovenous anastomosis and functions in thermal regulation. Case presentation A 24-year-old woman with a 6-month history of swelling in the left floor of her mouth was referred to our institution. She experienced slight difficulty in swallowing, she did not experience pain or tongue paralysis. Immunohistochemistry revealed that the tumor cells yield positive results for vimentin and alpha-smooth muscle actin, but negative results for desmin, anticytokeratin (AE) or AE3, cluster of differentiation (CD) and CD34, and S-100, and exhibited a Ki-67 index of 5%. These findings were consistent with those for a glomus tumor. The patient had an uneventful recovery with primary healing and had no evidence of recurrence over 4 years of follow-up
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