Abstract
>BACKGROUND:Global tuberculosis (TB) targets were set as part of the World Health Organization's End TB Strategy (2016–2035) and the Sustainable Development Goals (2016–2030).>OBJECTIVE:To define and explain the rationale for these targets.>DESIGN:Scenarios for plausible reductions in TB deaths and cases were developed using empirical evidence from best-performing countries and modelling of the scale-up of under-used interventions and hypothetical TB vaccines. Results were discussed at consultations in 2012 and 2013. A final proposal was presented to the World Health Assembly in 2014 and unanimously endorsed by all Member States.>RESULTS:The 2030 targets are a 90% reduction in TB deaths and 80% reduction in TB incidence compared with 2015 levels. The 2035 targets are for reductions of 95% and 90%, respectively. A third target—that no TB-affected households experience catastrophic costs due to the disease by 2020—was also agreed.>CONCLUSION:The global TB targets and milestones set for the period 2016–2035 are ambitious. Achieving them requires concerted action on several fronts, but two things are fundamental: 1) progress towards universal health coverage to ensure that everyone with TB can access high-quality treatment; and 2) substantial investment in research and development for new tools to prevent TB disease among the approximately 1.7 billion people infected.
Highlights
Deaths and 80% reduction in TB incidence compared with 2015 levels
The global TB targets and milestones set for the period 2016–2035 are ambitious
The dynamic model suggested that with a background of a 2% annual decline in TB incidence and a CFR of 16% combined with the MTS intervention, the number of TB deaths could fall by 22–65% by 2025 (Figure 5)
Summary
Deaths and 80% reduction in TB incidence compared with 2015 levels. The 2035 targets are for reductions of 95% and 90%, respectively. A third target—that no TBaffected households experience catastrophic costs due to the disease by 2020—was agreed. CONCLUSION : The global TB targets and milestones set for the period 2016–2035 are ambitious. Achieving them requires concerted action on several fronts, but two things are fundamental: 1) progress towards universal health coverage to ensure that everyone with TB can access high-quality treatment; and 2) substantial investment in research and development for new tools to prevent TB disease among the approximately 1.7 billion people infected.
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