Global patterns and temporal trends of perfluoroalkyl substances in municipal wastewater: A meta-analysis

Abstract

Despite increasing regulatory efforts to reduce production of per- and polyfluoroalkyl substances (PFAS), continued human and ecological exposure to PFAS has led to concerns about historical releases. Municipal wastewater treatment plants (WWTPs) provide important conduits between waste sources and the environment. We present a meta-analysis of results reported in 44 peer-reviewed publications that include 460 influent and 528 effluent samples, collected from 21 countries, for which some or all of five perfluorinated carboxylic acids (PFCAs) and three perfluorinated sulfonic acids (PFSAs) were measured. Our meta analysis revealed global patterns and trends that, to our knowledge, have not been reported elsewhere. Regression analyses of samples collected from 2004 to 2020 quantified the temporal trends of global wastewater effluent concentrations of each of the PFAS and the corresponding mean concentration for each country. Although legacy compounds, perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS), have been reported with the highest measured concentrations, their global temporal trends are lowest of all PFAS considered. Concentrations of most PFAS analyzed in wastewater in the United States have not changed significantly with time, whereas reported PFAS concentrations in wastewater effluent from China have increased from 11% to 37% per year. In addition, our results show significant positive correlations between previous wastewater effluent concentrations of individual PFAS and the gross domestic product per capita of each country. Our analysis of this global data set also confirmed conclusions from previous studies on smaller data sets: (i) none of the PFAS studied are effectively removed by conventional treatment processes; (ii) effluents from treatment plants that include a significant industrial component to their influent tend to have higher PFAS concentrations; and (iii) the few studies that measured both aqueous concentrations and concentrations adsorbed to suspended particulate matter (SPM) indicate that PFAS adsorbed to SPM can contribute significantly to the total PFAS load.