Abstract

Global Health: Role of HPV Testing in Resource Poor Environment Eighty-five percent of cervical cancer deaths occur in the developing world. While cervical cancer is only the tenth most common cancer in women in developed countries, it is the leading cause of cancer related deaths in women in low and middleincome countries (LMICs). Despite this, there is a disproportionate allocation of cervical-cancer related resources in countries with the highest burden. Cervical cancer is preventable and amenable to early detection and treatment. Over the past two decades, largescale data investigating low cost screening interventions have demonstrated efficacy of cervical cancer prevention in many continents.

Highlights

  • Eighty-five percent of cervical cancer deaths occur in the developing world

  • Clinical trials have found that HPV vaccination (Gardasil, Gardasil 9, Cerverix) is at least 95% effective in preventing HPV-16 or -18 persistent infection, and at least 93% effective in preventing vaccine-type specific lesions when given to girls prior to onset of sexual activity, or to those without prior infection with these subtypes [1,2,3]

  • The data demonstrates that the HPV vaccine is widely accepted in low and middleincome countries (LMICs)

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Summary

Introduction

Eighty-five percent of cervical cancer deaths occur in the developing world. While cervical cancer is only the tenth most common cancer in women in developed countries, it is the leading cause of cancer related deaths in women in low and middleincome countries (LMICs). Human papillomavirus; HPV; Low and middle income countries; LMIC; HPV testing; Cervical cancer screening Cervical cancer screening with VIA has been an inexpensive intervention that has been used worldwide in resource poor regions.

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