Abstract
Background: The global prevalence and disability of skin and subcutaneous diseases have grown annually in recent decades. Large-scale epidemiologic data is useful for better characterization of skin disease to create more impactful and sustainable interventions.
 Methods: We assessed multiple global trends in skin and subcutaneous disease from 1990 to 2017 in 195 countries worldwide through the latest Global Burden of Disease Study results from 2017.
 Results:Skin and subcutaneous disease grew 46.8% between 1990 to 2017 and is ranked fourth by incidence of all causes of disease. There is global variation in disease burden when stratified by age, sex, geographic regions, and sociodemographic index. Many global regions experience disproportionately elevated disease burden from certain subcategories of skin and subcutaneous disease. Wealthier countries generally experienced the highest age-standardized disability rates of skin and subcutaneous disease.
 Conclusion: The incidence, prevalence, and disability of skin and subcutaneous diseases are increasing disproportionately among countries and sociodemographic groups. This data may improve our understanding of skin and subcutaneous diseases to direct funding and resources to reduce global disparities.
Highlights
Skin and subcutaneous diseases are highly prevalent and one of the greatest contributors to disease morbidity in the world
Across all disease categories measured by the Global Burden of Disease (GBD), skin and subcutaneous disease ranked ninth in 2017 when measured by years lost due to disability (YLD), with an annual percent increase from 1990 to 2017 of 40.2% (Table 1)
Females experience greater age-specific prevalence rates of skin disease on a global scale until about the age of 70, where the trend was seen to reverse with a slight male predominance (Figure 1)
Summary
Skin and subcutaneous diseases are highly prevalent and one of the greatest contributors to disease morbidity in the world. Skin and subcutaneous diseases involve the global interaction of a variety of factors that impact regional disease morbidity. Analyzing these trends on a large scale may improve our understanding of the risk factors and characteristics of skin and subcutaneous diseases to direct funding and resources to reduce global disparities through more impactful and sustainable interventions. The global prevalence and disability of skin and subcutaneous diseases have grown annually in recent decades. Large-scale epidemiologic data is useful for better characterization of skin disease to create more impactful and sustainable interventions
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
